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KMID : 0371619990150010049
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Journal of Wonkwang Medical Science
1999 Volume.15 No. 1 p.49 ~ p.52
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Changes of Serum Electrolyte Concentrations by Succinylcholine Administration in Cerebral Palsy and Poliomyelitis Patients
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Lee Kang-Chang
Lee Hwan-Bong
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Abstract
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Background: Succinylcholine(Sch)-induced hyperkalemia occurs in patients with burn, severe trauma, uremia and neuromuscular diseases. Cerebral palsy and poliomyelitis are categorized into these neuromuscular diseases. This study was to exam the change of serum electrolyte after the administration of Sch in patients with cerebral palsy and poliomyelitis.
Materials and Methods: 60 patients were devided into three groups. Group 1 (n=20) was composed of cerebral palsy patients with age range 1-4years. Group 2 (n=20) was composed of cerebral palsy patients over 4 years. Group 3(n=20) was composed of patients with poliomyelitis. To establish the effect of Sch in patients with cerebral palsy and poliomyelitis, serum potassium, sodium, calcium and chloride were measured prior to administration of Sch, and 2, 5, 10 and 30 minutes after injection of it.
Results: Fine fasciculation on the hand (grade 1 by Cullen’s grading) occurred 4, 6, 13 in Group 1, 2 and 3, respectively. In Group 3, 2 patients showed minimal contraction of the trunk and extremities. There was no significant increase in the concentrations of potassium after the administration of Sch.
Conclusion: Succinylcholine seems to have no relation to hyperkalemia in patients with cerebral palsy and poliomyelitis over 1 year.
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KEYWORD
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Ions, potassium, hyperkalemia, Neurologic disorders, cerebral palsy, poliomyelitis, Neuromuscular relaxant, succinylcholine
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